The Fool card is the unnumbered card. The first or last card of the Major Arcana in Tarot.
It is the card of beginnings, innocence, light heartedness, and simply put faith. When this card comes up it's telling you to just jump in and take that leap of faith.
The 8 of Pentacles is the card of new ideas, new jobs, new activities, new hobbies. Or as one deck puts it the card of "apprentice".
I just did a short reading and these two cards came up in the start and end positions of the reading. The Fool was the first card in the spread, the 8 of Pentacles the end result.
I'm using a really beautiful deck today, called the Dreamer's Journal Tarot.